Dr. K News: Autoimmune diet
Lectins in grains and legumes
Grains and legumes are also high in lectins. Lectins have been shown to degrade the intestinal barrier. Once in the bloodstream they may bind to insulin receptors and leptin receptors (leptin acts in concert with insulin to control appetite). Some believe lectins may also have the ability to desensitize these receptors, thus contributing to insulin resistance and leptin resistance.