Low Carb Research
The past few decades have been enlightening in terms of scientific knowledge about low carb diets. The research which highlights the safety, indeed the necessity in some cases, and the efficacy of carbohydrate restriction can no longer be denied or ignored. Section Links: 2011 | 2010 | 2009 | 2008 | 2007| 2006 | 2005
2011
- A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation. Victor W. Ho, Kelvin Leung, Anderson Hsu, Beryl Luk, June Lai, Sung Yuan Shen, Andrew I. Minchinton, Dawn Waterhouse, Marcel B. Bally, Wendy Lin, Brad H. Nelson, Laura M. Sly, and Gerald Krystal
- A ketogenic diet suppresses seizures in mice through adenosine A1 receptors. Susan A. Masino, Tianfu Li, Panos Theofilas, Ursula S. Sandau, David N. Ruskin, Bertil B. Fredholm, Jonathan D. Geiger, Eleonora Aronica and Detlev Boison2
- Metabolic management of brain cancer. Thomas N. Seyfried, Michael A. Kiebish, Jeremy Marsh, Laura M. Shelton, Leanne C. Huysentruyt, and Purna Mukherjee
- Low-Carbohydrate Diet Review : Shifting the Paradigm. Adele H. Hite, MAT; Valerie Goldstein Berkowitz, MS, RD, CDE and Keith Berkowitz, MD, MBA
2010
- Limited Effect of Dietary Saturated Fat on Plasma Saturated Fat in the Context of a Low Carbohydrate Diet. Forsythe CE, Phinney SD, Feinman RD, Volk BM, Freidenreich D, Quann E, Ballard K, Puglisi MJ, Maresh CM, Kraemer WJ, Bibus DM, Fernandez ML, Volek JS
- Low carbohydrate ketogenic diet prevents the induction of diabetes using streptozotocin in rats. A. Al-Khalifaa, T.C. Mathewb, , , N.S. Al-Zaidc, E. Mathewa and H. Dashtid
- Ketogenic diet slows down mitochondrial myopathy progression in mice. Sofia Ahola-Erkkila, Christopher J. Carroll, Katja Peltola-Mjosund, Valtteri Tulkki, Ismo Mattila, Tuulikki Seppanen-Laakso, Matej Oresic, Henna Tyynismaa and Anu Suomalainen
- Long-term outcomes of children treated with the ketogenic diet in the past. Amisha Patel, Paula L. Pyzik, Zahava Turner, James E. Rubenstein, Eric H. Kossoff
- Type 1 diabetes and epilepsy: Efficacy and safety of the ketogenic diet. Anastasia Dressler, Eva Reithofer, Petra Trimmel-Schwahofer, Katrin Klebermasz, Daniela Prayer, Gregor Kasprian, Birgit Rami, Edith Schober, Martha Feucht
- Neuroprotective and Anti-inflammatory Activities of Ketogenic Diet on MPTP-induced Neurotoxicity. Xinxin Yang and Baohua Cheng
- Use of the modified Atkins diet for adolescents with chronic daily headache. EH Kossoff,J Huffman, Z Turner and J Gladstein
- Targeting Energy Metabolism in Brain Cancer with Restricted Diets. Thomas N. Seyfried, Michael A. Kiebish and Purna Mukherjee
- Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report. Giulio Zuccoli, Norina Marcello, Anna Pisanello, Franco Servadei, Salvatore Vaccaro, Purna Mukherjee and
Thomas N Seyfried - Red meat and colorectal cancer: a critical summary of prospective epidemiologic studies. D. D. Alexander and C. A. Cushing
- Weight and Metabolic Outcomes After 2 Years on a Low-Carbohydrate Versus Low-Fat Diet. Gary D. Foster, PhD; Holly R. Wyatt, MD; James O. Hill, PhD; Angela P. Makris, PhD, RD; Diane L. Rosenbaum, BA; Carrie Brill, BS; Richard I. Stein, PhD; B. Selma Mohammed, MD, PhD; Bernard Miller, MD; Daniel J. Rader, MD; Babette Zemel, PhD;
Thomas A. Wadden, PhD; Thomas Tenhave, PhD; Craig W. Newcomb, MS; and Samuel Klein, MD - In the face of contradictory evidence: Report of the Dietary Guidelines for Americans Committee. Adele H. Hite M.A.T. a, Richard David Feinman Ph.D., Gabriel E. Guzman Ph.D., Morton Satin M.Sc., Pamela A. Schoenfeld R.D. e, Richard J. Wood Ph.D.
- Low-Carbohydrate Diets Promote a More Favorable Body Composition Than Low-Fat Diets. Volek, Jeff S PhD, RD; Quann, Erin E PhD, RD; Forsythe, Cassandra E PhD, RD
- Low-fat diet fails to improve insulin sensitivity in metabolic syndrome. Joanna Lyford
- Saturated Fatty Acids and Risk of Coronary Heart Disease: Modulation by Replacement Nutrients. Patty W. Siri-Tarino, Qi Sun, Frank B. Hu and Ronald M. Krauss
- Resistance training in overweight women on a ketogenic diet conserved lean body mass while reducing body fat. Pal T Jabekk1, Ingvild A Moe, Helge D Meen, Sissel E Tomten, Arne T Høstmark
- Are refined carbohydrates worse than saturated fat? AJCN, April 21, 2010, Frank B. Hu
- Carbohydrate intake and cardiometabolic risk factors in high BMI African American children Sushma Sharma, Lindsay S Roberts, Robert H Lustig and Sharon E Fleming Nutrition & Metabolism 2010, 7:10doi:10.1186/1743-7075-7-10 Feb. 9, 2010
- Over-stimulation of insulin/IGF-1 signaling by Western diet may promote diseases of civilization: lessons learnt from Laron syndrome. Bodo C Melnik, Swen Malte John and Gerd Schmitz
2009
- A Very Low-Carbohydrate Diet Improves Symptoms and Quality of Life in Diarrhea-Predominant Irritable Bowel Syndrome. Gregory L. Austin, Christine B. Dalton, Yuming Hu, Carolyn B. Morris, Jane Hankins, Stephan R. Weinland, Eric C. Westman, William S. Yancy Jr, Douglas A. Drossman
- Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature. Bryan D Kraft and Eric C Westman
- Promoting Endurance Training Adaptations with Nutritional Interventions: The Potential Benefits of ‘Low Carbohydrate’ Training. Barry Drust and James P. Morton
- Effects of a Low Carbohydrate Weight Loss Diet on Exercise Capacity and Tolerance in Obese Subjects. Grant D. Brinkworth, Manny Noakes, Peter M. Clifton and Jonathan D. Buckley
- Low-carbohydrate diets reduce lipid accumulation and arterial inflammation in guinea pigs fed a high-cholesterol diet. Jose O. Leite, Ryan DeOgburn, Joseph Ratliff, Randy Su, Joan A. Smyth, Jeff S. Volek, Mary M. McGrane, Alan Dardik, Maria Luz Fernandez
- A Very Low-carbohydrate Diet Improves Symptoms and Quality of Life in Diarrhea-Predominant Irritable Bowel Syndrome. Gregory L. Austin, Christine B. Dalton, Yuming Hu, Carolyn B. Morris, Jane Hankins, Stephan R. Weinland, Eric C. Westman, William S. Yancy, Jr., and Douglas A. Drossman
- Renal Function Following Long-Term Weight Loss in Individuals with Abdominal Obesity on a Very-Low-Carbohydrate Diet vs High-Carbohydrate Diet. Grant D. Brinkworth, PhD, Jonathan D. Buckley, PhD, Manny Noakes, PhD, Peter M. Clifton, PhD
- Effects of dietary carbohydrate restriction vs low-fat diet on flow-mediated dilation. Jeff S. Volek, Kevin D. Ballard, Ricardo Silvestre, Daniel A. Judelson, Erin E. Quann,
Cassandra E. Forsythe, Maria Luz Fernandez, William J. Kraemer - Eggs distinctly modulate plasma carotenoid and lipoprotein subclasses in adult men following a carbohydrate-restricted diet. Gisella Mutungi, David Waters, Joseph Ratliff, Michael Puglisi, Richard M. Clark, Jeff S. Volek, Maria Luz Fernandez
- Macronutrient intakes and cardio metabolic risk factors in high BMI African American children.
Sushma Sharma, Lindsay S Roberts, Mark L Hudes, Robert H Lustig and Sharon E Fleming Nutrition & Metabolism 2009, 6:41doi:10.1186/1743-7075-6-41 Oct 13, 2009
- Protein hydrolysates in sports nutrition
- Effects of a low-carbohydrate diet on glycemic control in outpatients with severe type 2 diabetes Hajime Haimoto, Tae Sasakabe, Kenji Wakai and Hiroyuki Umegaki
Nutrition & Metabolism 2009 - Uncontrolled diabetes increases the risk of Alzheimer’s disease: a population-based cohort study Diabetologia, June, 2009
- A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
- Carbohydrate Restriction, as a First-Line Dietary Intervention, Effectively Reduces Biomarkers of Metabolic Syndrome in Emirati Adults Taif Al-Sarraj, Hussein Saadi, Mariana C. Calle, Jeff S. Volek and Maria Luz Fernandez (abstract)
- Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet
Richard J. Wood, Michael J. Puglisi, William J. Kraemer, Doug M. Bibus Maria Luz Fernandez, Richard D. Feinman - A 6-Month, Office-Based, Low-Carbohydrate Diet Intervention in Obese Teens
- Metabolic Syndrome and Changes in Body Fat From a Low-fat Diet and/or Exercise Randomized Controlled Trial
2008
- A Call for Higher Standards of Evidence for Dietary Guidelines. Paul R. Marantz, MD, MPH, Elizabeth D. Bird, AB, Michael H. Alderman, MD
- Carbohydrate restriction and cardiovascular risk. Jocelyne G. Karam, Fiby Nessim, Samy I. McFarlane and Richard D. Feinman
- Low-carbohydrate diet in type 2 diabetes: stable improvement of bodyweight and glycemic control during 44 months follow-up. Jörgen V Nielsen and Eva A Joensson
- Low-carbohydrate, high-protein diets revisited. Kushner, Robert F; Doerfler, Bethany
- Effects of Continuous Low-carbohydrate Diet after Long-term Exercise on GLUT-4 Protein Content in Rat Skeletal Muscle. M. Kubota, K. Koshinaka, Y. Kawata, T. Koike, Y. Oshida
- Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women. Backes AC, Abbasi F, Lamendola C, McLaughlin TL, Reaven G, Palaniappan LP
- Dietary Cholesterol from Eggs Increases Plasma HDL Cholesterol in Overweight Men Consuming a Carbohydrate-Restricted Diet. Gisella Mutungi, Joseph Ratliff, Michael Puglisi, Moises Torres-Gonzalez, Ushma Vaishnav, Jose O. Leite, Erin Quann, Jeff S. Volek and Maria Luz Fernande
- Eggs modulate the inflammatory response to carbohydrate restricted diets in overweight men. Joseph C Ratliff, Gisella Mutungi, Michael J Puglisi, Jeff S Volek and
Maria Luz Fernandez - Dietary Carb Restriction Research PLR 2008
- A reappraisal of the impact of dairy foods and milk fat on cardiovascular disease risk
- Carbohydrate Restriction Reduces Lipids and Inflammation and Prevents Artherosclerosis in Guinea Pigs
- Analysis of dietary interventions. A simple payoff matrix for display of comparative dietary trials Richard D Feinman, Eugene J Fine, Jeff S Volek Nutrition Journal 2008 7:24
- Weight Loss on a Low Carbohydrate, Mediterreanean or Low Fat Diet
- Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome Jeff S. Volek, Maria Luz Fernandez , Richard D. Feinman , Stephen D. Phinney
- Comparison of Low Fat and Low Carbohydrate Diets on Circulating Fatty Acid Composition and Markers of Inflammation
2007
- The Ketogenic Diet: One Decade Later. John M. Freeman, MD, Eric H. Kossoff, MD, Adam L. Hartman, MD
- Arguments in favor of ketogenic diets The Internet Journal of Nutrition & Wellness
- Low-carbohydrate nutrition and metabolism Review Article, The American Journal of Clinical Nutrition Eric C Westman, Richard D Feinman, John C Mavropoulos, Mary C Vernon, Jeff S Volek, James A Wortman, William S Yancy and Stephen D Phinney
2006
- The Effects of a Low-Carbohydrate Ketogenic Diet and a Low-Fat Diet on Mood, Hunger, and Other Self-Reported Symptoms F. Joseph McClernon, William S. Yancy, Jr., Jacqueline A. Eberstein, Robert C. Atkins and Eric C. Westman
- Non-alcoholic fatty liver disease and the metabolic syndrome: Effects of weight loss and a review of popular diets. Are low carbohydrate diets the answer? Harjot K Gill, George Y Wu
- LCD in family practice What we can learn from an internet support group
2005 and older
- Dietary protein intake and renal function William F Martin†1, Lawrence E Armstrong†2 and Nancy R Rodriguez Nutrition & Metabolism 2005, 2:25 doi:10.1186/1743-7075-2-2
- A Randomized Trial of a Low-Carbohydrate Diet vs Orlistat Plus a Low-Fat Diet for Weight Loss
- Efficacy of the Atkins diet as therapy for intractable epilepsy
- Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women Bonnie J. Brehm, Randy J. Seeley, Stephen R. Daniels, and David A. D'Alessio University of Cincinnati and Children’s Hospital Medical Center, Cincinnati, Ohio 45221
- A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet To Treat Obesity and Hyperlipidemia, A Randomized, Controlled Trial William S. Yancy Jr., MD, MHS; Maren K. Olsen, PhD; John R. Guyton, MD; Ronna P. Bakst, RD; and Eric C. Westman, MD, MHS
- Study Shows Low-Carb Diet Improves Cholesterol Eric Westman, MD,William Yancy, Jr., M.D., Maren Olsen, Ph.D., Tara Dudley and John Guyton, M.D., all of Duke University.
- Effects of a low-carbohydrate diet on weight loss and cardiovascular risk factor in overweight adolescents Stephen B. Sondike MD, Nancy Copperman MS, RD and Marc S. Jacobson MD From the Division of Adolescent Medicine, Schneider Children's Hospital
- New Duke Findings Corroborate Earlier Studies Demonstrating Benefits of Low-Carb Diet
- University of Connecticut Studies Indicate Ketosis is Safe Volek, JS, et al.: A Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal-Weight Men. Journal of Nutrition, July 2002.
- Saturated Fat Does Not Pose Heart Disease Risk in Healthy Men David Gilbert
- The low fat/low cholesterol diet is ineffective Correspondence: Dr. Laura A. Corr, MB, BS, MRCP, PhD, FESC, Consultant Cardiologist
- "A calorie is a calorie" violates the second law of thermodynamics The principle of "a calorie is a calorie," that weight change in hypocaloric diets is independent of macronutrient composition, is widely held in the popular and technical literature, and is frequently justified by appeal to the laws of thermodynamics. Richard D Feinman*1 and Eugene J Fine1,2
