Extract:
"...In some cases GS can present with normal or milder enteropathy seen as increased intestinal permeability, IBS, abdominal discomfort, pancreatic disorders, pain or diarrhoea; or it may present with a variety of extraintestinal symptoms including lymphoma, attention deficit disorder and neuropathy, autism and schizophrenia, infertility, IBD, muscular disturbances as well as osteopenia and osteoporosis..."For me, the money shot is really this bolded line:
"As CD with milder enteropathy is the most common form, histology cannot be considered as the gold standard any longer."Therefore, treatment should target the symptoms and not the immunohistology.Treat the symptoms - not the test. If you suspect any issue with gluten anywhere on the spectrum of possibility, take it out for a period of time and see how you feel. I really see little point in someone feeling better being gluten free but being given the green light to eat the stuff because they threw a negative tTg test... And parts of this review also call into question the common instruction given by doctors and dietitians to not exclude gluten from the diet as this makes it harder to diagnose via biopsy.
The information here really makes a mockery of many of the recent 'gluten is a fad' articles.
