Definition of Advanced Glycation Endproducts (AGEs) and the consequences of AGE accumulation.
Elevated blood glucose causes Glycation/Advanced Glycation Endproducts (AGEs) through two distinctive pathways: the Maillard reaction/glycation and the oxidative pathway.
Effects of Advanced Glycation Endproducts (AGEs). AGEs play a key role in the development of chronic age related diseases such as diabetes, renal failure, atherosclerosis and Alzheimer's disease. In particular AGEs are involved in the development of the cardiovascular complications of diabetes and renal failure.
Glycation, diabetes, and atherosclerosis
looks like the glycation theory of disease has been around for over a decade - a quick google search produced these hits:
glycation cancer - Google Scholar
glycation atherosclerosis - Google Scholar
Protein Glycation, Diabetes, and Aging -- Ulrich and Cerami 56 (1): 1 -- Recent Progress in Hormone Research
Protein glycation, diabetes, and aging. [Recent Prog Horm Res. 2001] - PubMed result
Lipid glycation and protein glycation in diabetes and atherosclerosis. | Mendeley
Advanced glycation end products and vascular infla... [Cardiovasc Res. 2004] - PubMed result
Amazon.com: The Glycation Hypothesis of Atherosclerosis (Medical Intelligence Unit) (9780412114915): Camilo A. L. S. Colaco: Books
Amazon.com: Camilo A. L. S. Colaco: Books, Biography, Blog, Audiobooks, Kindle
Amazon.com: The Glycation Hypothesis of Atherosclerosis (Medical Intelligence Unit) (9783540628545): Camilo A.L.S. Colaco: Books
Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis
Advanced Glycosylation End Products Might Promote Atherosclerosis Through Inducing the Immune Maturation of Dendritic Cells -- Ge et al. 25 (10): 2157 -- Arteriosclerosis, Thrombosis, and Vascular Biology
Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
Protein Glycation, Diabetes, and Aging -- Ulrich and Cerami 56 (1): 1 -- Recent Progress in Hormone Research
Advanced Glycosylation End Products Might Promote Atherosclerosis Through Inducing the Immune Maturation of Dendritic Cells -- Ge et al. 25 (10): 2157 -- Arteriosclerosis, Thrombosis, and Vascular Biology
Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
