Asthma Triggering Compounds from Omega-6 Fat Create Clogged Arteries
Bottomline: Excellent review paper, which describes how the potent inflammatory compounds, which trigger asthma, also damage arteries, via the leukotrienes generated from the omega-6 fat, arachidonic acid. Cardiovasc Drugs Ther. 2008 Oct 24. [Epub ahead of print]
Summary: This review paper describes the accumulating body of evidence, demonstrating how leukotrienes, the powerful group of eicosanoids, infamous for damaging lungs and triggering asthma, are also involved in heart disease. The key stages of arterial damage are described, beginning with irritation of the blood vessels linings, resulting in plaque accumulation and ultimately the potentially deadly rupture of the plaque (as depicted above).
Summary: This review paper describes the accumulating body of evidence, demonstrating how leukotrienes, the powerful group of eicosanoids, infamous for damaging lungs and triggering asthma, are also involved in heart disease. The key stages of arterial damage are described, beginning with irritation of the blood vessels linings, resulting in plaque accumulation and ultimately the potentially deadly rupture of the plaque (as depicted above).
