12.6.11

Attacking the Atkins diet - John McDougall, M.D.

an attack on the Atkin diet written by:
Wikipedia: "John A. McDougall, M.D., is an American physician and author whose philosophy is that degenerative disease can be prevented and treated with a diet of whole, unprocessed, low-fat plant foods, especially starches such as potatoes, rice, and beans, and which excludes all animal foods (except honey) and vegetable oils."
McDougall's philosophy is controversial and Quackwatch lists his newsletter as one of the non-recommended ones that "promote misinformation, espouse unscientific theories, contain unsubstantiated advice, are insufficiently skeptical, and/or fail to distinguish between reliable and unreliable sources of advice."
[and]: 54kzone.......beyond low carb: "I think that is kind of silly" - MacDougall rebuff

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The Atkins Scientific Research – Deceit and Disappointment

by John McDougall, M.D. 
published in the The McDougall Newsletter, May 2004

John A. McDougall, M.D. is a Board Certified internist who has authored several bestselling books on nutrition and is founder and medical director of the McDougall Program.

During the Great Nutrition Debate held February 24, 2000, by the United States Department of Agriculture in Washington D.C., Dr. Robert Atkins, founder of the world’s most famous low-carbohydrate diet plan, was challenged for his lack of medical research to support his claims, especially about the benefits of his high-fat, high-cholesterol diet for heart disease. Dr. Atkins responded, “And I haven't been able to fund the study.” Dr. Keith-Thomas Ayoob, associate professor of nutrition at Albert Einstein College of Medicine, New York continued his cross examination, “Excuse me. Excuse me. Ten million books in print, and you can't fund the study?”

Dr. Atkins responded, “Now I can, and I will be the first doctor to dig into his own pocket to do a study…” And he made true on his promise and since has funded sufficient research to persuade doctors, media personalities (like Neal Cavuto of Fox News Channel), and as many as 15% of the population of the USA, to believe that eating pork rinds, fried cheese, and lobster dripping in butter is good for body, heart, and soul – and that his previous 35 years of diet claims were right all along.

Dr. and Mrs. Atkins established the Dr. Robert C. Atkins Foundation in 1999, and thus far have endowed it with $3 million in grants – furthermore, the organization that bears their name, Atkins Nutritionals Inc., has a yearly income of $100 million; therefore, money for supportive research should be no barrier. Over the past three years several published studies, laced with sufficient bites of truth to influence the practice of medicine, have indeed been published. The consequences have been so profound that the Atkins Diet is now taught to medical students as part of their first year medical curriculum at the New York Downstate Medical Center in Brooklyn.25 These impressionable students learn that replacing potatoes with beefsteak protects against the development of heart disease and that the diet is a safe and effective solution to America’s obesity epidemic.25 The time has come for a thorough review of this research and a challenge to those who would distort the truth, often at the expense of your health.

The Science behind Atkins

I have spared no effort to locate and carefully read the scientific papers that have been published about the Atkins Diet. The ones that have received most public attention are those directly comparing the Atkins Diet to a “low-fat” diet. Of the nine research papers1-9 I was able to obtain and review that directly compare the Atkins Diet with a “low-fat” diet, four4,6-8 were funded by the Robert C. Atkins Foundation. Other research papers funded by the Atkins Foundation were also located and reviewed; 10-12 as were several others on this topic with independent financial support.13-20 The funding for the third issue of the journal of Metabolic Syndrome and Related Disorders was not identified, but the entire edition was dedicated to the memory of Robert Atkins, MD – and by no coincidence, the articles within were highly supportive of his low-carbohydrate diet.21-32 There were a few abstracts (a brief written paragraph about an unpublished study) and several related research papers in obscure journals that I could not obtain – I doubt that these would have altered my findings.

Ten Conclusions I Reached after Reviewing the Scientific Research Published on the Atkins Diet:

1) Use of the Term “Low-fat” in the Comparisons Is Dishonest

Researchers have deceived the public by claiming they have compared the Atkins Diet with a “low-fat” diet. The truth is all of their comparisons are with a calorie-restricted (portion-controlled) version of the typical American diet, containing approximately 30% of the calories as fat.1-9 The “dieting” (calorie-restricted, portion-controlled) approach to weight loss has a consistent history of failure; therefore, choosing this kind of diet for comparison greatly increases the odds that the Atkins Diet will appear favorable.

2) Long-Term Weight Loss Is Insignificant

Over the short-term (weeks), people on the Atkins Diet lose more weight than on the calorie-restricted diet, but this benefit does not last. After one year, the difference in weight lost between those following the Atkins Diet and those on the calorie-restricted diet was found to be statistically insignificant by the only two studies performed for this period of time.1,2

3) A Real Low-Fat Diet Is Far More Effective

Direct comparison of a truly low-fat diet (10% or less of the calories from fat) with the Atkins approach is long overdue. Available evidence supports superior benefits with a low-fat diet.33-34 A low-fat diet (and exercise) is the only approach found to provide long-term successful weight loss (an average of more than 70 pounds of weight lost per person and maintained for more than 6 years, based on a population of over 4,000 people).35-37

4) The “Metabolic Advantage” Is Nothing to Brag About

Over the short-term, the Atkins Diet will cause more weight loss, for the same number of calories consumed, as a calorie-restricted diet. This is referred to as the “metabolic advantage” of the low-carbohydrate diet. When the body is burdened with the wrong fuel (a diet of fat and protein, and insufficient carbohydrate) it must make changes that are metabolically expensive, thus burning extra calories.27 Better stated, the burden of the Atkins Diet requires the body to make adaptations originally intended for survival; in order to stay alive under this adversity.

5) The Atkins Diet Worsens Some Important Risk Factors for Heart Disease

The Atkins Diet consistently raises total and “bad “LDL-cholesterol, whereas, a calorie-restricted (30% fat) diet lowers these important predictors of future heart trouble.1,2,18 A truly low-fat diet (10% or less of calories from fat) is even more effective at reducing these risk factors than the 30% fat diets used for these comparisons.38-41

6) The Atkins Diet Improves Some Less Important Risk Factors for Heart Disease

The Atkins Diet lowers triglycerides (a less important risk factor), but so does a healthfully designed low-fat diet. “Good” HDL-cholesterol is increased1,2,4,7,8 on the Atkins Diet, but homocysteine (which predicts more heart disease) is also increased.17 When it comes to “heart health,” triglyceride and HDL-cholesterol values are of questionable importance and far less significant than total- and LDL-cholesterol.42,43 But to read the research paid for by Atkins you would think otherwise.4,6-8

7) Atkins Is Harder to Follow Long-term

Dropout rates are very high with both the Atkins and calorie-restricted diets, because both programs are very hard to follow. The Atkins Diet causes people to become “sick” and the calorie-restricted diet causes them to suffer the pains of hunger. When comparing these two unpleasant living conditions, the authors of the most recent one-year study published in the Annals of Internal Medicine raised “the possibility that the Atkins Diet was less sustainable.”2 In other words, constant sickness is more difficult to endure than the everyday pains of hunger.

8) Exercise Is Not an Easy Addition to the Atkins Program

Exercise is not a part of most of the research studies performed. 1-9 On a low-carbohydrate diet people are too fatigued to participate in increased physical activity.

9) Adverse Effects Are Common, Expected, and Sometimes Serious on Atkins

Most of the people following the Atkins Diet suffer adverse effects like constipation, fatigue, headaches, muscle cramps, diarrhea, and bad breath. Predictors of future health problems, such as elevated cholesterol, BUN, uric acid, and free fatty acids, are found with this diet.1-20 Furthermore, people have been reported to suffer from serious complications, such as dehydration, cardiac arrhythmias, kidney damage, kidney stones, liver, brain, and eye damage and also death from following high protein and ketogenic diets.2,4,14,18,44-55

10) Atkins Is Not Accepted by the Scientific Community – for Good Reasons

Major health organizations, for example, the American Heart Association Nutrition Committee, warn the public that the kinds of foods encouraged by the Atkins Diet will increase their risk of health problems.44


For the Curious Reader Further Explanation and Support of My Findings Follows

Comparing Atkins with a “Low-fat” Diet is Deceptive

All of the papers purporting the comparison of the Atkins Diet with a “low-fat” diet have deceived the public – and their authors must have known better.1,3-9 The “low-fat” diet used is actually approximately 30% of the calories from fat in all cases. Consider, the average American eats a diet with 32% to 38% of calories coming from fat. In each case the diet that is labeled “low-fat” is in truth the conventional, always-known-to-fail, calorie-restricted diet. In one of the major studies,3 before the diet began the participants’ diets were 33% fat; the goal was to reduce to 30% fat – but in the end their “low-fat” diets actually contained 33% of the calories as fat (the same as before they started) – so where is the low-fat part of the comparison alleged by the title of the article? – “A low-carbohydrate as compared with a low-fat diet in severe obesity.”

For the short-term (6 to 24 weeks) the Atkins approach betters the calorie-restricted diet by 4 to 12 pounds (2 to 5.5 Kg).4 Some of this early weight loss (up to 8 pounds) reflects water loss (from diuresis and loss of glycogen stores). However, at 12 months, research financed independent of Atkins has found the difference in weight loss to be insignificant (2.1 Kg or less).1,2 The reason people fail to continue to lose weight on the Atkins Diet is primarily because of lack of adherence to the diet. Interestingly, researchers from one of the long-term studies reported those on the calorie-restricted diet who dropped out continued to lose the same amount of weight as those who stayed in the study, whereas those in the Atkins group were less likely to lose weight if they dropped out. This finding, along with the weight gains that were seen between 6 and 12 months on the Atkins Diet led researchers to raise the possibility that the Atkins Diet was less sustainable (than the portion controlled, calorie-restricted diet).2 (I believe the reason Dr. Atkins, himself was so grossly overweight was, not because of the lack of effectiveness of a ketogenic diet, but because even he could not follow his own diet for long.)

The Atkins Diet is inherently difficult to stick with because of the underlying mechanism for weight loss – the diet makes people sick. Followers of this kind of diet complain of reduced appetite, nausea, and fatigue – all symptoms of illness, which result in a natural reduction in daily food intake – which includes consuming fewer calories. You can only stay sick for so long before you long for relief and return to eating more carbohydrates and less fat.

A Low-fat Diet Solves the Obesity Epidemic

A low-fat diet as used by Kempner (the Rice Diet), Pritikin, Ornish, McDougall, and Barnard is based on plant foods and contains 10% or less of the calories from fats of all kinds. Except for the Kempner Diet, all of these truly low-fat diets emphasize unrefined foods consumed in unlimited amounts (ad libitum). A recent review of 28 trials using lower-fat, higher-carbohydrate diets found a 10% reduction in fat resulted in a 6.3 pound (2.88 Kg) weight loss sustained over 6 months.56 When the researchers in another study allowed the dieters to eat as much as they wanted of a diet containing 18% fat, along with exercise, the results were: an 11 pound (4.8 Kg) weight loss, and without exercise, the same diet resulted in a 7 pound (3.2 Kg) weight loss, over 12 weeks.57 Another study of sixty-four healthy post-menopausal women on a low-fat diet (11% fat) for 8 months found an average 13 pound (6 Kg) weight loss.58 The composition of these low-fat diets reflect the diets of people living in rural communities in Africa, the Middle East, and the Far East – which means a starch-based diet followed by millions of people living without obesity, type-2 diabetes, coronary heart disease, and the cancers common to Western societies.59

The most relevant information on successful weight loss comes from the National Weight Control Registry.35-37 Successful dieters have been tracked by this study since 1993. The registry is simply a database of people successful at maintaining a weight loss of at least 30 lbs. (13.6 kg) for at least one year. However, the average registrant has lost 70 pounds (32 kg) and kept it off for 6 years. To date, there are over 4,000 people, from all over the United States, enrolled in the National Weight Control Registry.

On average, registrants report consuming about 1400 kcal/day (24 percent calories from fat) and expending about 400 calories/day in physical exercise. Approximately 80% of the registrants eat less than 30% fat, and 35% eat less than 20% fat. Although they may have lost their initial weight by a variety of methods, including liquid protein diets, on their own, or through an organized program, all are currently maintaining their weight losses by eating low-energy, low-fat diets and engaging in regular physical activity. About 50 percent of participants lost weight on their own without any type of formal program or help.

The “Metabolic Advantage” of the Atkins Diet

The rationale for the Atkins Diet is that severe carbohydrate restriction will result in ketosis which promotes lipid oxidation (fat loss), satiety (satisfaction of appetite), and increased energy expenditure. Supporters of the Atkins low-carbohydrate Diet promote this approach as a faster, more efficient way to lose weight than other diets. They believe there is an increased weight loss per calorie compared to other similar diets, higher in carbohydrate. They refer to this phenomenon as the “metabolic advantage.”27 The increase in energy loss is due to inefficiency in body metabolism caused by the low-carbohydrate diet. For example, the human body on a very low-carbohydrate diet has to expend energy to make carbohydrate for tissues that absolutely require glucose, like the brain and red blood cells (through the process of gluconeogenesis, glucose is synthesized from protein) – this means extra calories are expended. This is only one of many calorie-requiring adaptions to survive that occur when the body is forced to live without sufficient carbohydrate.

I believe that following the Atkins Diet does cause the body to become inefficient and to expend more calories – but this transformation is not something to brag about. Gluconeogenesis is a metabolic pathway used naturally during times of duress when people are not eating, because of starvation or sickness. Since the brain, red blood cells, and a few other tissues must have carbohydrate to function, the body must call upon this mechanism to survive. If increasing calorie expenditure by taxing the body’s survival mechanisms were truly the proper direction for the diet industry to head, then might not the next generation of weight loss programs include infecting people with dysentery, malaria or HIV? There is no question that the short-term (dysentery and malaria) and long-term (HIV) weight losses will outstrip even the sickness-associated-weight-loss caused by Atkins.

However, not all studies find this “metabolic advantage” and the recent 24-week study published in the Annals of Internal Medicine (paid for by the Robert C. Atkins Foundation) found the percentage of total weight lost that was from fat over 24 weeks was similar in the Atkins and “low-fat,” calorie-restricted, diet groups.4

Flawed Research Used to Promote the “Metabolic Advantage” – And They Know Better

Promoters of the concept of the “metabolic advantage” of the Atkins Diet are so desperate to make their point that they will use obviously bogus research, and describe this work as the “most striking” evidence.27 This spectacular evidence for the “metabolic advantage,” collected by Stephen Sondike, was published in 2003 in the journal Pediatrics.9

The work by Sondike is a 12-week, randomized, controlled study of 39 children, aged 12 to 18, placed on either the Atkins Diet or “low-fat” (actually 30% fat) diet.9 The results: those on the Atkins Diet lost 12.8 pounds (5.8 Kg) more than those on the “low-fat diet,” while consuming many more calories each day on the Atkins Diet. Calculated from the difference in daily calories – 1830 on Atkins minus 1100 on “low-fat” – there would have been a 730 calorie per day “metabolic advantage” if both groups had lost same amount of weight.

However, both groups did not lose the same weight – the Atkins people actually lost 12.8 pounds more than the “low-fat” group – so these calories must be accounted for also. These 12.8 pounds of weight loss mean an additional deficit of 532 calories per day (12.8 pounds x 3500 calories/pound of fat / 84 days = 532 calories per day). Adding these two differences together (730 plus 532 calories) would mean that the Atkins Diet in this study had a “metabolic advantage” of 1262 calories a day – that’s more calories than the children on the “low-fat” diet were said to eat daily. This is obviously impossible – and any one interested in honest research would know that, and completely discount these findings. Worse than deceiving the public, this flawed study is shamelessly used to instruct medical students on the benefits of the Atkins Diet.25

The Big Lie: Eating Steak Cuts Your Risk of Heart Disease (That’s What They Tell Medical Students25 and the Public).

The fact is, eating fat and cholesterol increases your risk of dying of heart disease, strokes and other forms of atherosclerosis (kidney failure and peripheral vascular diseases) – and all major health organizations and almost all doctors and scientists agree.44 All well-designed studies show the total cholesterol and “bad” LDL cholesterol both increase with the Atkins Diet.1,2,18 The May 2004 study, financed by Atkins and published in the Annals of Internal Medicine, described two participants in the low-carbohydrate diet group (Atkins) who dropped out of the study because of concerns about elevated serum lipid levels.4 In one participant, the LDL-cholesterol level increased from 184 mg/dl (4.75 mmol/l) to 283 mg/dl (7.31 mmol/l) in 3 months. Another participant’s LDL-cholesterol level went from 182 mg/dl (4.70 mmol/l ) to 219 mg/dl (5.66 mmol/l) in 4 weeks. Overall, LDL-cholesterol increased by more than 10% in 30% of the people on the low-carbohydrate diet.4 (Ideally, LDL-cholesterol should be well below 100 mg/dl, and probably, even below 80 mg/dl for people concerned about heart disease.)

The spin Atkins promoters use to minimize the impact of these negative findings is to point out the Atkins Diet lowers triglycerides, raises “good” HDL-cholesterol, and increases the amount of “less dense” LDL-cholesterol. Both triglycerides and HDL-cholesterol are considered of much less importance than total- and LDL-cholesterol in predicting the future risk of artery disease. For example, in the well-respected studies on the reversal of heart disease by Dr. Dean Ornish, participants showed reversal on his very-low fat diet, while at the same time their triglycerides increased and their HDL-cholesterol levels decreased.42 In the most important study yet published on the reversal of artery disease using cholesterol-lowering medications (like Lipitor), researchers found that “good” HDL-cholesterol played no role in predicting the condition of the arteries (growth of plaques).43

Their final effort to right the heart-disease-promoting wrongs of the Atkins Diet is to focus on the size of LDL-cholesterol. Some studies show the larger the LDL-cholesterol particles in the blood, the less the risk of heart disease in a population. The size of LDL-cholesterol is tied directly to both triglycerides and HDL-cholesterol. If you agree with me that these two values are of little value in predicting the effects of diet on real-life artery disease, then the LDL-cholesterol particle size cannot be the saving grace for the Atkins Diet.60 Furthermore, a very low-fat diet improves the LDL-particle size without the adverse consequences on blood cholesterol caused by the Atkins Diet.39

“The Atkins Diet Does Not Increase Heart Disease” – So They Say

Studies comparing the effects of the Atkins Diet and a relatively high-cholesterol, 30% fat, calorie-restricted diet show, on average, the Atkins Diet increases total cholesterol by about 2%, and LDL-cholesterol by 3% -- whereas, the “low-fat” diet lowers these values by 6 % and 9%, respectively. You may wonder why doubling the saturated fat and cholesterol in the diet by switching to Atkins doesn’t make even a worse impact on the blood lipids (cholesterol). There are two important reasons for these unexpected findings.

First, the body has tremendous capacity to adapt to extraordinary living conditions in order to survive. When the fat intake becomes extreme, as it does with the Atkins Diet, the excess fat interferes with the intestinal absorption of cholesterol in some, but not all, individuals.61 Also, the first 200 to 400 mg of cholesterol consumed completely saturates the capacity of the gut to absorb cholesterol, so any additional is left behind in the intestine, to be excreted.62 When subjects are already consuming 30% fat, and 300 mg to 500 mg of cholesterol, as they are on their pre-Atkins, typical American diet, then little additional impact is caused by further increases when switching to the Atkins Diet. Obviously, meaningful information cannot be gained about the true impact of the Atkins Diet on the body by comparing it with a calorie-reduced version of a diet that kills more than two-thirds of its followers prematurely in the first place, the rich Western diet.

Second, the Atkins Diet works by making people sick. As mentioned above, followers of this kind of diet complain of reduced appetite, nausea, and fatigue – all symptoms of illness, which result in a natural reduction in daily food intake. Expected consequences of eating smaller amounts of red meat, poultry, fish, and cheese – basic components of these low-carbohydrate diets – are that people consume less saturated fat, cholesterol, sodium, animal protein, and fewer calories. Signs of improved health seem to appear because risk factors, like cholesterol, triglycerides, uric acid, glucose, blood pressure, and body weight decrease – and the patient is declared healthier. Not necessarily so. Similar benefits, for similar reasons, are seen when patients are placed on cancer chemotherapy – and doctors don’t brag about these results.63

Confirmation of this “semi-starvation” mechanism of the Atkins Diet for improved risk factors comes from the results of research on young people with seizure disorders, treated with a ketogenic diet (like Atkins), who are encouraged to eat sufficient calories to maintain their body weight. Under these circumstances, all risk factors – including cholesterol, LDL-cholesterol, and triglycerides – increase dramatically (and HDL-cholesterol decreases).14

In simplest terms, low-carbohydrate diets exaggerate consumption of the unhealthiest components of the Western diet (animal protein and fat) to a level that makes people sufficiently ill to lose their desire to eat – and expected changes follow. The alternative is to encourage people to eat foods that promote both ideal body weight and health – those from a high-carbohydrate, low-fat diet.33,34

Finally, this entire subject of risk factors must be placed in proper perspective. Risk factors, like the level of cholesterol in the blood, are not diseases, but rather bits of information that help to foretell one’s future health. No one dies of high-cholesterol – rather, they die of diseased arteries – but because the same foods that raise cholesterol also damage the arteries, the two are commonly associated. Therefore, because this is an association, rather than a cause-and-effect relationship, it is important to realize that improving the values of risk factors may not necessarily translate into improved health – this is obviously true if the means for changing these values is inherently unhealthy, like feeding a diet of pork rinds, fried hamburger patties, and lobster dripping in butter to people; i.e. the Atkins Diet.

Real Damage from Atkins Would Be Seen with Honest Comparisons

To determine the true impact of the Atkins Diet on blood cholesterol, a comparison must be made with a truly low-fat (10% or less), no-cholesterol diet. Two studies of people following very low-cholesterol diets suggest what will be found: When subjects following a low-cholesterol diet (97 mg/day) were fed one egg a day (an additional 321 mg of cholesterol) their “bad” LDL-cholesterol increased by 12%.64 By comparison, the egg industry has funded numerous studies to “prove” eating eggs does not raise cholesterol – they accomplish this by feeding eggs to subjects whose intestines are already fully saturated with cholesterol from their regular diet – so they are able to absorb little more.65

A group of Tarahumara Indians from Northern Mexico was switched from their traditional diet of corn, beans, squash and other vegetables (2700 calories, 16% fat and trace cholesterol) to an American diet (4100 calories, 44% fat, and 1020 mg cholesterol) for five weeks.66 These changes were seen in their blood:

Total cholesterol increased 31% (121 to 159 mg/dl)

LDL-cholesterol increased by 39% (72 to 100 mg/dl)

HDL-cholesterol increased by 31% (32 to 42 mg/dl)

Triglycerides increased by 18% (91 to 108 mg/dl)

(Note that eating an unhealthy diet with more fat and cholesterol increases all fractions of cholesterol, including “good” HDL-cholesterol.)

Long-term benefits of a low-fat diet have been seen with the Ornish and Pritikin groups.40,41,67 Six month results from the very low-fat diet used by Dr. Ornish found significantly greater reductions in anginal (chest pain) frequency, body weight, body mass index, systolic blood pressure, total cholesterol, low-density lipoprotein cholesterol, and glucose, than in a cardiac rehabilitation group using the standard Heart Association (30% fat) diet.40

Results of a study of 4587 adults who attended a 3-week residential Pritikin Program using a very low-fat diet, showed total cholesterol was reduced by 23% (234 to 180 mg/dl) and LDL-cholesterol was reduced by 23% (151 to 116 mg/dl).41 Follow-up studies for 18 months on a small group of these people showed that, in most cases, continued compliance with the program maintained total cholesterol values well below 200 mg/dl.

The Atkins Diet: Short-term Weight Loss – While Sacrificing Health

The research says the Atkins Diet makes people sick. The most recent study paid for by the Robert C. Atkins Foundation found three of the 59 participants in the Atkins group dropped out; 2 because of a rise in LDL-cholesterol and one because of shakiness and uneasiness.4 Many troublesome problems occurred frequently in the low-carbohydrate diet (Atkins) group:4

Symptom (% of patients complaining)

Constipation (68%)

Headache (60%)

Halitosis (38%)

Muscle cramps (35%)

General weakness (25%)

Diarrhea (23%)

Rash (13%)

One participant sought medical attention for constipation, but had no complications. One 53-year-old man with a family history of early heart disease developed chest pain near the end of the study, and coronary heart disease was subsequently diagnosed.4 In the Samaha study (not financed by Atkins) one patient was hospitalized with chest pain and one patient died while on the low-carbohydrate, Atkins Diet.3

Other reported adverse effects of a low-carbohydrate/ketogenic diet include:

* Increased fat and cholesterol increases the blood cholesterol and risk of heart attacks.44

* Increased fat increases the long-term risk of obesity.45

* Increased dietary fat has been linked to various common cancers.46

* Increased dietary protein and acid increases the risk of kidney stones and osteoporosis.47,48

* Free fatty acids, which increase the risk of heart (cardiac) arrhythmias double.18

Cardiac arrhythmias have been observed on the diet.18

* Uric acid, creatinine and BUN increase, which reflect an increased workload on the kidneys and a prediction of future kidney failure.2

* Patients complain of fatigue, thirst, lassitude, bad taste, and foul breath.18

* Increased depression, anger, confusion, fatigue and decreased vigor.49-51

* Neuropsychological tests show worsening performance when people are on a ketogenic diet (like Atkins).52

* Damage to the eyes (optic neuropathy) has been seen with a ketogenic diet.53

Special Problems for Children (The diet is recommended for children by Atkins and others.9,20)

* Long-term adherence to a low-carb (ketogenic) diet may cause permanent damage to the developing brain.54

* Short-term effects include hypoglycemia, vomiting, diarrhea, dehydration, and refusal to eat; long-term effects include irritability, lethargy, kidney stones, acidosis, hyperuricemia, hypocalcemia, decreased amino acids, growth, and hypercholesterolemia.14
* Serious adverse events were experienced by five children (10% of the group): severe hypoproteinemia, lipemia (excess triglycerides in the blood), and hemolytic anemia, Fanconi's renal tubular acidosis; and two children manifested marked increases in liver function tests.55
* Long-standing ketosis has been associated with myocardial dysfunction (heart problems) in children.56 Of twenty patients on the ketogenic diet, 3 had EKG abnormalities (prolonged QT interval) and three patients had evidence of cardiac chamber enlargement. In one patient with severe dilated cardiomyopathy and EKG abnormalities, these problems normalized when the diet was discontinued.56

Also understand that the foods recommended on a low-carbohydrate diet are primarily meat, poultry, fish, and cheeses. Over 90% of the environmental chemicals, such as DDT, dioxin, and PCB – substances known to cause cancer and damage to your nervous system – enter your body through these foods (not plant-foods). Also realize that these same animal foods carry microbes known to infect people, including bovine leukemia viruses, the “mad-cow” agent, E. coli, salmonella, tuberculosis, and listeria, to name a few well-known threats to your health.

You Can Have Weight Control and Health, Too

The overwhelming popularity of low-carbohydrate diets and the acceptance of supportive scientific research are largely because Atkins is speaking to the choir – people love to hear good news about their bad habits. “Just tell me I will lose weight and avoid heart disease and diabetes by eating more eggs, cheese, lobster, and steak.” But that is not the truth and deep down inside even the current followers of Atkins must know this. The overwhelming evidence clearly condemns the low-carb diet, and this approach should not be used for even short-term weight loss.

Don’t despair, there is a meal plan that will allow you good looks and good health – and that is a time-honored diet that most people who have ever walked this earth have consumed – a high-carbohydrate, low-fat diet, based on starches with the addition of fruits and vegetables. Leave the eggs for Easter, the ham for Christmas and the turkey for Thanksgiving – rather than eating these “Atkins delights” every meal, everyday, until you make yourself so sick you lose a little weight – then you quit and you regain your lost fat – just as the two, twelve-month-long studies on the Atkins Diet prove you will do.1,2